Product Overview
• Perindopril arginine 5 mg film-coated tablets • Angiotensin-converting enzyme inhibitor (ACEI) • Once-daily treatment for essential hypertension, heart failure, and cardiovascular risk reduction • Prescription-only medicine • Pack contains 30 tablets (3 blister strips of 10 – 1-month supply)
Product Description
Coversyl 5 mg Tablets contain perindopril arginine, a long-acting ACE inhibitor that reduces angiotensin II production, leading to vasodilation and lowered blood pressure. Indicated for essential hypertension (alone or in combination), stable coronary artery disease (reduction of cardiovascular events), and symptomatic heart failure. Provides smooth 24-hour blood pressure control with once-daily dosing and proven cardiovascular protection (EUROPA study – reduced risk of heart attack, stroke, and CV death). The arginine salt formulation improves stability and shelf life compared to erbumine salt. The 5 mg dose is a common maintenance dose or starting dose in combination therapy. Benefits • Effective 24-hour blood pressure control with single daily dose • Reduces risk of cardiovascular events in patients with stable coronary disease • Well tolerated with low incidence of side effects (especially cough vs older ACEIs) • Safe in elderly, diabetic, and renal-impaired patients (with dose adjustment) • Proven renal protective effects in hypertensive patients • Once-daily dosing improves compliance How to Use • Adults: usual starting dose 5 mg once daily in the morning • Hypertension: titrate to 10 mg if needed (maximum 10 mg) • Coronary artery disease: start 5 mg, increase to 10 mg after 2 weeks if tolerated • Elderly or renal impairment: start at 2.5 mg, maximum 5–10 mg • Swallow whole with water – preferably in the morning, with or without food • Can be combined with diuretics, calcium channel blockers, or beta-blockers • Regular blood pressure monitoring recommended • Persistent dry cough may occur – consult doctor if troublesome