Product Overview
• Fixed-dose combination antihypertensive tablet • Contains 10 mg amLodipine (as besylate) + 160 mg valsartan • Pack of 30 film-coated tablets for once-daily use • Prescription medication for adults with essential hypertension • Dual mechanism: calcium channel blocker + angiotensin II receptor blocker • Effective for patients not adequately controlled on monotherapy
Product Description
Lotevan 10mg/160mg Tablets combine amLodipine, a dihydropyridine calcium channel blocker that relaxes blood vessels, with valsartan, an angiotensin II receptor blocker that prevents vasoconstriction. This synergistic action provides superior blood pressure reduction compared to either drug alone, particularly in moderate to severe hypertension. It is indicated as substitution therapy in patients whose blood pressure is already controlled on amLodipine and valsartan separately at the same doses, or as initial therapy in high-risk patients. The combination reduces cardiovascular events and improves adherence with once-daily dosing. Benefits • Powerful 24-hour blood pressure control with single tablet • Reduces risk of stroke, heart attack, and kidney damage • Well-tolerated with lower incidence of peripheral edema than amLodipine alone • Improves arterial compliance and endothelial function • Suitable for patients with diabetes or metabolic syndrome • Convenient fixed-dose simplifies treatment regimen How to Use • Take one tablet once daily at the same time, with or without food • Swallow whole with water – do not crush or chew • Can be taken with other antihypertensives if needed • Initial dose for most patients; no titration required • Regular blood pressure monitoring recommended • Do not stop suddenly – consult doctor for dose adjustments • Seek medical help if dizziness, swelling, or chest pain occurs