Product Overview
• Metronidazole 500 mg film-coated tablets • Nitroimidazole antibiotic and antiprotozoal agent • Effective against anaerobic bacteria and certain parasites • Prescription-only medicine • Pack contains 20 tablets (2 blister strips of 10)
Product Description
Negazole 500 mg Tablets contain metronidazole, a broad-spectrum antimicrobial that disrupts DNA synthesis in susceptible anaerobic bacteria and protozoa. Indicated for treatment of bacterial vaginosis, trichomoniasis, amoebiasis (intestinal and extra-intestinal), giardiasis, anaerobic infections (intra-abdominal, skin/soft tissue, bone/joint, CNS), and surgical prophylaxis in anaerobic-contaminated procedures. Also used in Helicobacter pylori eradication regimens (with other antibiotics and PPI). Provides high tissue penetration and excellent efficacy against obligate anaerobes and protozoa. The 500 mg strength allows convenient twice- or thrice-daily dosing for most indications. Benefits: • Highly effective against anaerobic infections and protozoal diseases • Rapid symptom relief in bacterial vaginosis and trichomoniasis (often single-dose or short course) • Good penetration into abscesses, CNS, and bone • Essential component in H. pylori triple/quadruple therapy • Well tolerated short-term with food to reduce GI upset • Alternative for patients intolerant to other antibiotics in anaerobic coverage How to Use: • Adults: usual dose 400–500 mg 2–3 times daily or 2 g single dose (depending on indication) • Bacterial vaginosis/trichomoniasis: 2 g (4 tablets) single dose or 400–500 mg twice daily for 5–7 days • Anaerobic infections: 500 mg 3 times daily for 7–10 days • H. pylori: 500 mg twice daily with other agents for 7–14 days • Swallow whole with water – best taken with or after food • Avoid alcohol during treatment and for 48 hours after (disulfiram-like reaction risk) • Complete full course even if symptoms improve earlier