Olmedine Olmesartan & Amlodipine 40/10mg Blood Pressure Control Tablets 28s

• Olmedine 40mg/10mg Tablets – olmesartan medoxomil 40mg + amLodipine besylate 10mg (28 tablets) • Maximum-strength fixed-dose combination of ARB + calcium-channel blocker • Once-daily powerhouse for resistant or severe hypertension when lower doses are insufficient • Delivers average BP drop of 30–40/15–20 mmHg – one of the strongest oral combos available • Original Daiichi Sankyo formulation (same as Sevikar 40/10mg) • 28-tablet pack = convenient 1-month supply

Olmedine 40/10 combines the highest approved dose of olmesartan (the most potent ARB with longest half-life) with the highest standard dose of amLodipine. This synergy provides unmatched 24-hour blood-pressure control, especially in patients with high cardiovascular risk, diabetes, chronic kidney disease or previous stroke. Real-world studies (SEVITENSION, COACH) confirm superior efficacy vs up-titration of either drug alone, with excellent tolerability. Benefits • Maximum BP lowering from a single tablet • Once-daily – outstanding adherence • Reduced ankle swelling vs amLodipine 10mg alone (olmesartan counteracts fluid retention) • Strong kidney & heart protection profile • Proven to lower central aortic pressure (better than many other combos) • 28-tablet pack = perfect monthly refill for controlled patients How to Use • Adults: 1 tablet once daily (morning or evening), with or without food • Swallow whole – do not crush, split or chew • Usually prescribed after 20/5 or 40/5 strengths are not enough • Regular BP monitoring + kidney function/electrolytes check advised • Do not stop abruptly – taper if discontinuation needed • Store below 25°C in original packaging