Olmedine 40/5 mg combines a high-dose angiotensin II receptor blocker (ARB) with a low-dose calcium channel blocker (CCB) for powerful blood pressure control in patients whose hypertension is not adequately controlled on either drug alone. It is indicated for essential hypertension in adults. Benefits • Greater blood pressure reduction than either component alone • Once-daily dosing improves adherence • 24-hour smooth control – effective morning and night • Reduces risk of stroke, heart attack and kidney damage • Well tolerated – lower incidence of ankle swelling than higher-dose amLodipine • Proven efficacy in moderate to severe hypertension • Suitable for patients with diabetes or metabolic syndrome How to Use • Take one tablet once daily • Swallow whole with water – can be taken with or without food • Best taken at the same time each day (morning or evening) • Starting dose in most patients when combination needed • Can be increased to 40/10 mg if further control required • Regular blood pressure monitoring recommended • Continue low-salt diet and exercise