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Panadol Advance 500 mg Tablets (48s) is a fast-absorbing paracetamol pain reliever with OPTIZORB® technology, for everyday relief of pain and fever in adults and children aged 12 years and over.
Panadol Advance 500 mg Tablets 48s brings you Panadol's trusted paracetamol in an advanced formulation. Each film-coated tablet contains 500 mg of paracetamol made with patented OPTIZORB® technology, a delivery system that breaks the tablet down faster than standard paracetamol tablets so the medicine is released more efficiently. The 48-tablet pack is a convenient size for the home medicine cabinet, the office and travel.
How OPTIZORB® technology works
Standard paracetamol tablets must first dissolve before the body can absorb them. OPTIZORB® tablets disperse rapidly, releasing paracetamol up to 5 times faster than standard paracetamol tablets. Panadol Advance can start working in as little as 10 minutes and leaves the body naturally within 24 hours, with the safety profile you expect from Panadol.
What Panadol Advance relieves
Key features and benefits
How to use
Important safety information
Product details
Buy Panadol Advance 500 mg 48 tablets online in the UAE from Medon Pharmacy – a MoH-licensed online pharmacy with fast delivery across Dubai, Abu Dhabi and the Emirates.
Paracetamol 500 mg with OPTIZORB® technology – releases its medicine up to 5× faster than standard paracetamol tablets.

Patented OPTIZORB® technology breaks the tablet down faster than standard paracetamol tablets, releasing its medicine up to 5× faster so it can start working in as little as 10 minutes.

The advanced formula is designed to deliver paracetamol more efficiently: the tablet disperses quickly in the stomach instead of dissolving slowly, so the medicine is available for absorption sooner.
| Active ingredient | Paracetamol 500 mg |
|---|---|
| Pack size | 48 film-coated tablets |
| Suitable for | Adults and children 12 years and over |
| Dose | 1–2 tablets every 4–6 hours · max 8 in 24 hours |
| Prescription | Not required (over the counter) |
| Manufacturer | Haleon (GSK) |
| Storage | Below 30°C, protected from moisture |
Adults and children 12 years and over: 1–2 tablets every 4–6 hours as needed. Do not take more than 8 tablets (4 g of paracetamol) in 24 hours and leave at least 4 hours between doses.
Thanks to OPTIZORB® technology it releases its medicine up to 5 times faster than standard paracetamol tablets and can start working in as little as 10 minutes.
Either. Swallow the tablets with water, with or without food. Panadol Advance is gentle on the stomach when used as directed.
Adults and children from 12 years. It is not recommended for children under 10; for ages 10–12 follow the pack leaflet or ask our pharmacists about paediatric Panadol products.
Do not take it with any other product containing paracetamol. If you take other medicines or have liver or kidney problems, check with a pharmacist first.
Contains paracetamol. Do not take with other paracetamol-containing products. Always read the label and the patient information leaflet. Keep out of reach of children. If symptoms persist or worsen, consult your doctor or pharmacist.