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Panadol Extra with OPTIZORB® Formulation (48s) combines paracetamol 500 mg and caffeine 65 mg in a fast-dissolving tablet that releases its actives up to 5× faster and can start working in just 10 minutes.
Panadol Extra with OPTIZORB® Formulation 48s is the new, faster-dissolving Panadol Extra. Each film-coated tablet contains paracetamol 500 mg and caffeine 65 mg, made with OPTIZORB® technology so the tablet breaks down quickly and releases its active ingredients up to 5 times faster than standard tablets – it can start working in just 10 minutes. The 48-tablet pack is the value size for families and frequent users.
Why caffeine?
Caffeine increases the chances of achieving headache relief compared with paracetamol alone. Panadol Extra is clinically proven to provide more effective pain relief than standard paracetamol – up to 37% more powerful – and is particularly effective for headaches.
Fights 5 types of tough pain
Also relieves mild to moderate pain from rheumatism and musculoskeletal disorders, and the discomfort of influenza, feverishness and feverish colds.
Key features
How to use
Important safety information
Product details
Buy Panadol Extra 48 tablets online in the UAE from Medon Pharmacy – a MoH-licensed online pharmacy with fast delivery across Dubai, Abu Dhabi and the Emirates.
Paracetamol 500 mg + caffeine 65 mg in a new fast-dissolving formulation – up to 37% more powerful pain relief than standard paracetamol.

OPTIZORB® technology breaks the tablet down quickly, releasing paracetamol and caffeine up to 5× faster than standard tablets.

Paracetamol relieves pain and reduces fever; caffeine increases the chance of achieving pain relief compared with paracetamol alone. Together they are clinically proven to provide more effective pain relief than standard paracetamol.
| Active ingredients | Paracetamol 500 mg · caffeine 65 mg |
|---|---|
| Formulation | Film-coated tablets with OPTIZORB® technology |
| Pack size | 48 tablets |
| Suitable for | Adults and children 12 years and over |
| Dose | 1–2 tablets up to 4 times a day · at least 4 hours apart · max 8 in 24 hours |
| Prescription | Not required (over the counter) |
| Manufacturer | Haleon (GSK) |
The new formulation uses OPTIZORB® technology so the tablet dissolves faster and releases its active ingredients up to 5 times faster than standard tablets – it can start working in just 10 minutes.
Adults and children 12 years and over: 1–2 tablets up to 4 times a day, at least 4 hours apart. Do not take more than 8 tablets in 24 hours.
Caffeine increases the chance of achieving pain relief compared with paracetamol alone; Panadol Extra gives up to 37% more powerful pain relief than standard paracetamol. Avoid excessive caffeine from drinks while taking it.
Panadol Extra is not recommended for children under 12 years.
Do not take with any other paracetamol-containing product. Ask our pharmacist before combining with other medicines.
Contains paracetamol. Do not take with other paracetamol-containing products. Always read the label and the patient information leaflet. Keep out of reach of children. If symptoms persist or worsen, consult your doctor or pharmacist.