Product Overview
• Clopidogrel bisulfate 75 mg film-coated tablets • Antiplatelet agent (P2Y12 inhibitor) • Once-daily treatment for prevention of atherothrombotic events • Prescription-only medicine • Pack contains 28 tablets (4 blister strips of 7 – 1-month supply)
Product Description
Plavix 75 mg Tablets contain clopidogrel, a potent inhibitor of platelet aggregation that irreversibly blocks the P2Y12 ADP receptor on platelets, preventing clot formation. Indicated for secondary prevention of atherothrombotic events in adults with recent myocardial infarction (MI), ischaemic stroke, or established peripheral arterial disease (PAD). Also used in acute coronary syndrome (ACS) – with or without stenting – often in combination with aspirin. Provides sustained antiplatelet effect with once-daily dosing and proven reduction in cardiovascular events (CAPRIE, CURE, COMMIT studies). The 75 mg dose is the standard maintenance dose after optional loading dose (300 mg). Benefits • Reduces risk of heart attack, stroke, and cardiovascular death in high-risk patients • Essential in ACS and post-stent to prevent stent thrombosis • Once-daily dosing improves compliance • Proven efficacy when combined with aspirin (dual antiplatelet therapy) • Well tolerated long-term in most patients • Alternative for aspirin-intolerant patients How to Use • Adults: usual dose 75 mg once daily • Acute coronary syndrome: loading dose 300 mg (4 tablets), then 75 mg daily (often with aspirin) • Take with or without food • Swallow whole with water • Continue as prescribed – often long-term (12 months post-stent, lifelong in some cases) • Regular monitoring (bleeding risk) recommended • Avoid abrupt discontinuation – increased risk of thrombotic events • Inform doctor/dentist before surgery or procedures (may need temporary cessation)